Article
Glioma.
Nature reviews. Disease primers - 16 Jul 2015
Weller Michael, Wick Wolfgang, Aldape Ken, Brada Michael, Berger Mitchell, Pfister Stefan M, Nishikawa Ryo, Rosenthal Mark, Wen Patrick Y, Stupp Roger, Reifenberger Guido
Abstract excerpt
Gliomas are primary brain tumours that are thought to derive from neuroglial stem or progenitor cells. On the basis of their histological appearance, they have been traditionally classified as astrocytic, oligodendroglial or ependymal tumours and assigned WHO grades I-IV, which indicate different degrees of malignancy. Tremendous progress in genomic, transcriptomic and epigenetic profiling has resulted in new...
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