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Evidence of promiscuous endothelial binding by P lasmodium falciparum ‐infected erythrocytes

21 Jan 2014

Abstract excerpt

The adhesion of infected red blood cells (iRBCs) to human endothelium is considered a key event in the pathogenesis of cerebral malaria and other life-threatening complications caused by the most prevalent malaria parasite Plasmodium falciparum. In the past 30 years, 14 endothelial receptors for iRBCs have been identified. Exposing 10 additional surface proteins of endothelial cells to a mixture of P. falciparum...

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PMID: 24444337
DOI: 10.1111/cmi.12270

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