Article
Changing identities: tRNA duplication and remolding within animal mitochondrial genomes.
Proceedings of the National Academy of Sciences of the United States of America - 23 Dec 2003
Rawlings Timothy A, Collins Timothy M, Bieler Rudiger
Abstract excerpt
Although the majority of metazoan mitochondrial genomes (mtDNAs) contain the same 37 genes, including 22 encoding transfer RNAs (tRNAs), the recognition of orthologs is not always straightforward. Here we demonstrate that inferring tRNA orthologs among taxa by using anticodon triplets and deduced secondary structure can be misleading: through a process of tRNA duplication and mutation in the anticodon triplet,...
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