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Article

Transfer RNA identity change in anticodon variants of E. coli tRNA(Phe) in vivo.

Molecules and cells - 29 Feb 2000

Kim H S, Kim I Y, Söll D, Lee S Y

Abstract excerpt

The anticodon sequence is a major recognition element for most aminoacyl-tRNA synthetases. We investigated the in vivo effects of changing the anticodon on the aminoacylation specificity in the example of E. coli tRNA(Phe). Constructing different anticodon mutants of E. coli tRNA(Phe) by site-directed mutagenesis, we isolated 22 anticodon mutant tRNA(Phe); the anticodons corresponded to 16 amino acids and an opal...

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Share to Anticodon
Share to Cell Division
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Recombinant

Share to Mutagenesis, Site-Directed

Share to RNA, Transfer

Share to RNA, Transfer, Phe

Share to Transformation, Genetic

Source

Identifiers

PMID: 10774751
DOI: 10.1007/s10059-000-0076-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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