Article
Pleiotropic effects of HNF1A rs1183910 in a population-based study of 60,283 individuals.
Diabetologia - 1 Apr 2014
Allin Kristine H, Nordestgaard Børge G
Abstract excerpt
AIMS/HYPOTHESIS: According to genome-wide association studies (GWAS) a locus in the HNF1A gene has pleiotropic effects on several metabolic traits. In a large single-centre study we used the intronic variant rs1183910 located in a region with no or low recombination rate as an instrument for the HNF1A locus to evaluate pleiotropic effects of this locus on the risk of developing type 2 diabetes, as well as on body...
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