Article
Relationship between Plasmodium falciparum malaria prevalence, genetic diversity and endemic Burkitt lymphoma in Malawi.
Scientific reports - 17 Jan 2014
Johnston W Thomas, Mutalima Nora, Sun David, Emmanuel Benjamin, Bhatia Kishor, Aka Peter, Wu Xiaolin, Borgstein E, Liomba G N, Kamiza Steve, Mkandawire Nyengo, Batumba Mkume, Carpenter Lucy M, Jaffe Harold, Molyneux Elizabeth M, Goedert James J, Soppet Daniel, Newton Robert, Mbulaiteye Sam M
Abstract excerpt
Endemic Burkitt lymphoma (eBL) has been linked to Plasmodium falciparum (Pf) malaria infection, but the contribution of infection with multiple Pf genotypes is uncertain. We studied 303 eBL (cases) and 274 non eBL-related cancers (controls) in Malawi using a sensitive and specific molecular-barcode array of 24 independently segregating Pf single nucleotide polymorphisms. Cases had a higher Pf malaria prevalence...
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