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Article

A dual-targeted aminoacyl-tRNA synthetase in Plasmodium falciparum charges cytosolic and apicoplast tRNACys.

The Biochemical journal - 15 Mar 2014

Pham James S, Sakaguchi Reiko, Yeoh Lee M, De Silva Nilushi S, McFadden Geoffrey I, Hou Ya-Ming, Ralph Stuart A

Abstract excerpt

Plasmodium parasites possess two endosymbiotic organelles: a mitochondrion and a relict plastid called the apicoplast. To accommodate the translational requirements of these organelles in addition to its cytosolic translation apparatus, the parasite must maintain a supply of charged tRNA molecules in each of these compartments. In the present study we investigate how the parasite manages these translational...

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PMID: 24428730
DOI: 10.1042/BJ20131451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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