Article
Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation.
Molecular vision - 1 Jan 2014
Zhang Liyun, Ma Ping, Collery Ross, Trowbridge Sara, Zhang Mingzhi, Zhong Wenxuan, Leung Yuk Fai
Abstract excerpt
PURPOSE: The purpose of this study was to develop a framework for analyzing retinal pigment epithelium (RPE) expression profiles from zebrafish eye mutants. METHODS: The fish model we used was SWI/SNF-related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (smarca4), a retinal dystrophic mutant with a previously described retinal phenotype and expression profiles. Histological...
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