Article
Association of ADRA2A and MTHFR gene polymorphisms with weight loss following antipsychotic switching to aripiprazole or ziprasidone.
Human psychopharmacology - 1 Jan 2014
Roffeei Siti Norsyuhada, Reynolds Gavin P, Zainal Nor Zuraida, Said Mas Ayu, Hatim Ahmad, Aida Syarinaz Ahmad, Mohamed Zahurin
Abstract excerpt
OBJECTIVES: Various genetic polymorphisms have been reported to be associated with antipsychotic-induced weight gain. In this study, we aimed to determine whether risk polymorphisms in 12 candidate genes are associated with reduction in body mass index (BMI) of patients following switching of antipsychotics to aripiprazole or ziprasidone. METHODS: We recruited 115 schizophrenia patients with metabolic...
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