Article
Intermediate sized CGG repeats are not a common cause of idiopathic premature ovarian failure.
Human reproduction (Oxford, England) - 1 May 2010
Bennett Claire E, Conway Gerard S, Macpherson James N, Jacobs Patricia A, Murray Anna
Abstract excerpt
BACKGROUND: It is recognized that FMR1 premutation expansions are associated with premature ovarian failure (POF), but the role of smaller repeats at the boundary of premutation and normal is less clear. METHODS: We have therefore investigated the incidence of these intermediate sized FMR1 CGG repeats (35-58 repeats) in a series of 366 women ascertained because of menopause before the age of 40. RESULTS: We found...
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