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Article

Length of FMR1 repeat alleles within the normal range does not substantially affect the risk of early menopause.

Human reproduction (Oxford, England) - 1 Oct 2016

Ruth Katherine S, Bennett Claire E, Schoemaker Minouk J, Weedon Michael N, Swerdlow Anthony J, Murray Anna

Abstract excerpt

STUDY QUESTION: Is the length of FMR1 repeat alleles within the normal range associated with the risk of early menopause? SUMMARY ANSWER: The length of repeat alleles within the normal range does not substantially affect risk of early menopause. WHAT IS KNOWN ALREADY: There is a strong, well-established relationship between length of premutation FMR1 alleles and age at menopause, suggesting that this relationship...

Topics

Adult
Alleles
Cross-Sectional Studies
Female
Fragile X Mental Retardation Protein
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Menopause

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Menopause, Premature

Middle Aged

Trinucleotide Repeats

Source

Open in PubMed Open full text

Identifiers

PMID: 27614355
DOI: 10.1093/humrep/dew204
PMCID: PMC5027929

Genes

FMR1
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Length of FMR1 repeat alleles within the normal range does not substantially affect the risk of early menopause.PMID 27614355Read ↗

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