Article
kruX: matrix-based non-parametric eQTL discovery.
BMC bioinformatics - 14 Jan 2014
Qi Jianlong, Asl Hassan Foroughi, Björkegren Johan, Michoel Tom
Abstract excerpt
BACKGROUND: The Kruskal-Wallis test is a popular non-parametric statistical test for identifying expression quantitative trait loci (eQTLs) from genome-wide data due to its robustness against variations in the underlying genetic model and expression trait distribution, but testing billions of marker-trait combinations one-by-one can become computationally prohibitive. RESULTS: We developed kruX, an algorithm...
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