Article
P-values in genomics: apparent precision masks high uncertainty.
Molecular psychiatry - 1 Dec 2014
Lazzeroni L C, Lu Y, Belitskaya-Lévy I
Abstract excerpt
Scientists often interpret P-values as measures of the relative strength of statistical findings. This is common practice in large-scale genomic studies where P-values are used to choose which of numerous hypothesis test results should be pursued in subsequent research. In this study, we examine P-value variability to assess the degree of certainty P-values provide. We develop prediction intervals for the P-value...
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