Article
Rhabdomyosarcoma: Updates on classification and the necessity of molecular testing beyond immunohistochemistry.
Human pathology - 1 May 2024
Dehner Carina A, Rudzinski Erin R, Davis Jessica L
Abstract excerpt
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents under the age of 20. The current World Health Organization (WHO) classification for soft tissue and bone tumors recognizes 4 distinct subtypes of RMS based on clinicopathological and molecular genetic features: embryonal, alveolar, spindle cell/sclerosing and pleomorphic subtypes. However, with the increased use of molecular...
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