Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic analysis of HIV-1 proviral genomes from infected individuals: Predominance of unmethylated CpG's

5 Dec 2013

Abstract excerpt

Efforts to cure HIV-1 infections aim at eliminating proviral DNA. Integrated DNA from various viruses often becomes methylated de novo and transcriptionally inactivated. We therefore investigated CpG methylation profiles of 55 of 94 CpG's (58.5%) in HIV-1 proviral genomes including ten CpG's in each LTR and additional CpG's in portions of gag, env, nef, rev, and tat genes. We analyzed 33 DNA samples from PBMC's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24418551
DOI: 10.1016/j.virol.2013.11.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic analysis of HIV-1 proviral genomes from infected individuals: Predominance of unmethylated CpG'sPMID 24418551Read ↗

Source of CpG Depletion in the HIV-1 GenomeSemantic proximity Read ↗

In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirusSemantic proximity Read ↗

Deciphering DNA Methylation in HIV InfectionSemantic proximity Read ↗

Epigenome-wide differential DNA methylation between HIV-infected and uninfected individualsSemantic proximity Read ↗

Longitudinal variation in human immunodeficiency virus long terminal repeat methylation in individuals on suppressive antiretroviral therapySemantic proximity Read ↗

HIV Coreceptors Related Genes (CCR5 and CXCR4) Promoter Methylation: Original ResearchSemantic proximity Read ↗

Latency-associated DNA methylation patterns among HIV-1 infected individuals with distinct disease progression courses or antiretroviral virologic responseSemantic proximity Read ↗

Paucity of HIV DNA Methylation in Latently Infected, Resting CD4 + T Cells from Infected Individuals Receiving Antiretroviral TherapySemantic proximity Read ↗

Epigenetic crosstalk in chronic infection with HIV-1Semantic proximity Read ↗

Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ARTSemantic proximity Read ↗

5' long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signalsSemantic proximity Read ↗

Long-Term Nonprogressor and Elite Controller Patients Who Control Viremia Have a Higher Percentage of Methylation in Their HIV-1 Proviral Promoters than Aviremic Patients Receiving Highly Active Antiretroviral TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.