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Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals

13 Aug 2016

Abstract excerpt

Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral integration and latency. However, epigenetic changes in the HIV-1-infected host genome have not been well characterized. Here, we report the first large-scale epigenome-wide association study of DNA methylation for HIV-1 infection. We recruited HIV-infected (n = 261) and uninfected (n = 117) patients from the Veteran Aging...

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PMID: 27672717
DOI: 10.1080/15592294.2016.1221569

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