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Article

Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays.

Cancer science - 1 Mar 2014

Takita Junko, Chen Yuyan, Kato Motohiro, Ohki Kentaro, Sato Yusuke, Ohta Shigeru, Sugita Kanji, Nishimura Riki, Hoshino Noriko, Seki Masafumi, Sanada Masashi, Oka Akira, Hayashi Yasuhide, Ogawa Seishi

Abstract excerpt

Malignant rhabdoid tumor (MRT) is a rare and highly lethal cancer that mainly affects infants and young children. The majority of MRT are characterized by loss of function of SMARCB1 on chromosome 22q11.2. However, little is known about genetic changes other than SMARCB1 alterations that are responsible for the development and/or progression of MRT. To explore additional gene targets in MRT, we analyzed 21 MRT...

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Share to Chromosomal Proteins, Non-Histone
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to DNA Methylation

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Source

Open in PubMed Open full text

Identifiers

PMID: 24418192
DOI: 10.1111/cas.12352
PMCID: PMC4317948

Genes

SMARCB1
CNTNAP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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