Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic nicotine improves short-term memory selectively in a G72 mouse model of schizophrenia.

British journal of pharmacology - 1 Apr 2014

Hambsch B, Keyworth H, Lind J, Otte D M, Racz I, Kitchen I, Bailey A, Zimmer A

Abstract excerpt

BACKGROUND AND PURPOSE: The prevalence of smoking in schizophrenia patients is exceptionally high; it is not known why but many researchers suggest that smoking constitutes a form of self-medication. Among the symptoms of schizophrenia that may be improved by nicotine are cognitive deficits. Hence, we studied the effects of long-term nicotine administration on cognition in a genetic animal model of schizophrenia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha7 Nicotinic Acetylcholine Receptor
Share to Memory, Short-Term

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neural Inhibition

Share to Nicotine

Share to Nicotinic Agonists

Share to Prosencephalon

Share to Recognition, Psychology

Share to Schizophrenic Psychology

Source

Open in PubMed Open full text

Identifiers

PMID: 24417347
DOI: 10.1111/bph.12578
PMCID: PMC3966754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic nicotine improves short-term memory selectively in a G72 mouse model of schizophrenia.PMID 24417347Read ↗

Schizophrenia-like phenotypes and long-term synaptic plasticity impairment in GluN2A-transgenic mice.Semantic proximity Read ↗

Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.Semantic proximity Read ↗

The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo.Semantic proximity Read ↗

Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers.Semantic proximity Read ↗

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.Semantic proximity Read ↗

Methamphetamine-induced locomotor sensitization in mice is not associated with deficits in a range of cognitive, affective and social behaviours: interaction with brain-derived neurotrophic factor Val66Met genotype.Semantic proximity Read ↗

Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.Semantic proximity Read ↗

Research tool: Validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches.Semantic proximity Read ↗

Disturbances of novel object exploration and recognition in a chronic ketamine mouse model of schizophrenia.Semantic proximity Read ↗

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn miceSemantic proximity Read ↗

Performance of F2 B6x129 hybrid mice in the Morris water maze, latent inhibition and prepulse inhibition paradigms: Comparison with C57Bl/6J and 129sv inbred mice.Semantic proximity Read ↗

Thyroid receptor β involvement in the effects of acute nicotine on hippocampus-dependent memory.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.