Article
The HIV 'A' (sor) gene product is essential for virus infectivity.
Nature - 1 Jan 2000
Strebel K, Daugherty D, Clouse K, Cohen D, Folks T, Martin M A
Abstract excerpt
The genome of the human immunodeficiency virus (HIV) contains several open reading frames (ORFs) not present in other viruses. The 'A' gene, also known as Q2 P'3, ORF-1(4) or sor5, partially overlaps the pol gene; its protein product has a relative molecular mass of 23,000 (Mr 23K) and is present in productively infected cells. The function of this protein is unclear; mutant viruses deleted in 'A' replicate in...
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