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Article

The HIV 'A' (sor) gene product is essential for virus infectivity.

Nature - 1 Jan 2000

Strebel K, Daugherty D, Clouse K, Cohen D, Folks T, Martin M A

Abstract excerpt

The genome of the human immunodeficiency virus (HIV) contains several open reading frames (ORFs) not present in other viruses. The 'A' gene, also known as Q2 P'3, ORF-1(4) or sor5, partially overlaps the pol gene; its protein product has a relative molecular mass of 23,000 (Mr 23K) and is present...

Topics

Amino Acid Sequence
Cell Communication
Chromosome Deletion
Cloning, Molecular
Colonic Neoplasms
Genetic Complementation Test
HIV
Humans
Mutation
Phenotype
RNA-Directed DNA Polymerase
Recombination, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Virion

Source

Identifiers

PMID: 2441266
DOI: 10.1038/328728a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2441266-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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