Article
Expression of genes related to energy metabolism (osteocalcin, FOXO1, insulin receptor, and SOST) in bone cells of Goto-Kakizaki rats and response to bariatric surgery.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery - 1 Jan 2000
Pérez-Castrillón Jose L, Riancho Jose A, de Luis Daniel, Gonzalez-Sagrado Manuel, Domingo-Andres María, Dueñas-Laita Antonio
Abstract excerpt
OBJECTIVES: The aim of this experimental study was to evaluate the expression of 4 genes (osteocalcin, sclerostin (SOST), insulin receptor, and transcription factor forkhead box protein (FOXO1) in the bone cells of Goto-Kakizaki (GK) rats and the expression of these genes in response to bariatric surgery. METHODS: We designed an experimental study with 3 arms (Wistar rats, nonoperated GK rats, and GK rats with...
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