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Article

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells.

Stem cell research & therapy - 17 Sept 2013

Al-toub Mashael, Almusa Abdulaziz, Almajed Mohammed, Al-Nbaheen May, Kassem Moustapha, Aldahmash Abdullah, Alajez Nehad M

Abstract excerpt

INTRODUCTION: Studying cancer tumors' microenvironment may reveal a novel role in driving cancer progression and metastasis. The biological interaction between stromal (mesenchymal) stem cells (MSCs) and cancer cells remains incompletely understood. Herein, we investigated the effects of tumor cells' secreted factors as represented by a panel of human cancer cell lines (breast (MCF7 and MDA-MB-231); prostate...

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Identifiers

PMID: 24405819
DOI: 10.1186/scrt325
PMCID: PMC3854757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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