Article
Acellular pertussis vaccine based on outer membrane vesicles capable of conferring both long-lasting immunity and protection against different strain genotypes.
Vaccine - 12 Feb 2014
Gaillard María Emilia, Bottero Daniela, Errea Agustina, Ormazábal Maximiliano, Zurita M Eugenia, Moreno Griselda, Rumbo Martin, Castuma Celina, Bartel Erika, Flores Dario, van der Ley Peter, van der Ark Arno, F Hozbor Daniela
Abstract excerpt
Despite high vaccination coverage rates, pertussis continues to be a global concern, with increased incidence widely noted. The current pertussis epidemiologic situation has been mainly attributed to waning immunity and pathogen adaptation. To improve the disease control, a new generation of vaccines capable to overcome those weaknesses associated to the current vaccines need to be developed. Previously we have...
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