Article
[Immunogenicity and safety of vaccine preparations based on circulating Bordetella pertussis strains].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Zaĭtsev E M, Mertsalova N Iu, Britsina M V, Ozeretskovskaia M N, Bazhanova I G, Shinkarev A S, Poddubikov A V
Abstract excerpt
AIM: Study specific activity and safety ofvaccine preparations based on circulating B. pertussis strains with currently predominating allele variants of pertussis toxin (ptxA1) and pertactin (prn2) genes. MATERIALS AND METHODS: B. pertussis strains isolated from pertussis patients in Moscow in 2001-2010 were grown in dense and liquid media. The content of separate antigens in B. pertussis strains was determined...
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