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Outer membrane vesicles derived from Bordetella pertussis are potent adjuvant that drive Th1-biased response

8 Apr 2024

Abstract excerpt

For several years, we have been committed to exploring the potential of Bordetella pertussis-derived outer membrane vesicles (OMVBp) as a promising third-generation vaccine against the reemerging pertussis disease. The results of our preclinical trials not only confirm its protective capacity against B. pertussis infection but also set the stage for forthcoming human clinical trials. This study delves into the...

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PMID: 38650936
DOI: 10.3389/fimmu.2024.1387534

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