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Article

Population dynamics and antigenic drift of Bordetella pertussis following whole cell vaccine replacement, Barcelona, Spain, 1986-2015.

Emerging microbes & infections - 1 Jan 2019

Mir-Cros Alba, Moreno-Mingorance Albert, Martín-Gómez M Teresa, Codina Gema, Cornejo-Sánchez Thais, Rajadell Mireia, Van Esso Diego, Rodrigo Carlos, Campins Magda, Jané Mireia, Pumarola Tomàs, Fàbrega Anna, González-López Juan José

Abstract excerpt

Among the factors associated with the resurgence of whooping cough, special emphasis has been given to pathogen adaptation after the introduction of the acellular vaccine (ACV). To assess the impact of the vaccine transition strategy from whole-cell vaccine (WCV) to ACV on population dynamics of Bordetella pertussis in Barcelona (Spain), we studied 339 isolates collected from 1986 to 2015 by PFGE and multi-locus...

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Identifiers

PMID: 31769735
DOI: 10.1080/22221751.2019.1694395
PMCID: PMC6882445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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