Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic effect of α-globin gene numbers on Indian sickle β-thalassemia patients.

Journal of clinical laboratory analysis - 1 Mar 2014

Pandey Sanjay Kumar, Pandey Sweta, Ranjan Ravi, Shah Vineet, Mishra Rahasya Mani, Sharma Monica, Saxena Renu

Abstract excerpt

BACKGROUND: Sickle cell β-thalassemia is a compound heterozygous state of β-thalassemia and sickle cell anemia. Patient with these conditions showed mild-to-severe clinical phenotype. OBJECTIVES: The objective of this study was to evaluate the effects of α-globin gene numbers on the phenotype of sickle cell β-thalassemia patients. MATERIALS AND METHODS: Seventy-five sickle cell β-thalassemia patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Globins
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Thalassemia

Share to Gene Dosage

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 24395608
DOI: 10.1002/jcla.21652
PMCID: PMC6807439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic effect of α-globin gene numbers on Indian sickle β-thalassemia patients.PMID 24395608Read ↗

Effect of deletions in the α-globin gene on the phenotype severity of β-thalassemia.Semantic proximity Read ↗

Alpha globin gene alterations modifying the phenotype of homozygous beta thalassaemiaSemantic proximity Read ↗

Alpha‐globin gene triplication and its effect in beta‐thalassemia carrier, sickle cell trait, and healthy individualSemantic proximity Read ↗

[Analysis of copy number variations in alpha-globin gene in the cases with combined increased levels of HbF with β thalassemia].Semantic proximity Read ↗

Frequencies and phenotypic consequences of association of α- and β-thalassemia alleles with sickle-cell disease in Bahrain.Semantic proximity Read ↗

Hematological Parameters in Individuals with Beta Thalassemia Trait in South Sumatra, IndonesiaSemantic proximity Read ↗

Alpha globin gene deletions in amelioration of clinical severity in beta haemoglobinopathy subjects with the β<sup>0</sup>/β<sup>+</sup> genotypeSemantic proximity Read ↗

α-globin Alteration in α-thalassemia Disorder: Prediction and Interaction Defect.Semantic proximity Read ↗

Descriptive profile of β-thalassemia mutations in West Bengal population: a hospital-based study.Semantic proximity Read ↗

Introduction of novel α1-hemoglobin gene mutation with transfusion-dependent phenotype.Semantic proximity Read ↗

Clinical, hematologic and molecular variability of sickle cell-β thalassemia in western IndiaSemantic proximity Read ↗

Correlation of beta-thalassemia mutations with alpha-thalassemia: an experience of the southwestern region of Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.