Article
α-globin Alteration in α-thalassemia Disorder: Prediction and Interaction Defect.
Pakistan journal of biological sciences : PJBS - 1 Jan 2017
Handayani Niken Satuti Nur, Husna Nailil, Sanka Immanuel
Abstract excerpt
BACKGROUND AND OBJECTIVE: The α-thalassemia is an inherited blood disorder affecting quality and quantity of hemoglobin. It caused mostly by deletion of one or two α-globin genes and characterized by deficient production of α-globin chain in hemoglobin leading from mild anemia to lethal. The α-globin gene with partial deletion could reduce chain production or produce abnormal chain. Its effect depends on...
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