Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Management of a Prostate Cancer Patient With Inherited Germline BRCA1 and BRCA2 Mutations: A Case Report.

Urology - 1 Jul 2021

Hemal Sij, DeWitt-Foy Molly, Klein Eric A

Abstract excerpt

The Breast Cancer Gene (BRCA) confers an 8.6-fold higher risk of developing prostate cancer in men ≤ 65 years of age and portends a worse prognosis as compared to noncarriers even in patients with low volume, localized disease. The BRCA2 gene, in particular, imparts a more biologically aggressive form of prostate cancer and a higher prostate cancer specific mortality. From a treatment standpoint, this translates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein
Share to Early Detection of Cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Medical History Taking

Share to Neoplasm Grading

Share to Organ Size

Share to Prostate

Share to Prostatectomy

Source

Identifiers

PMID: 33556450
DOI: 10.1016/j.urology.2020.11.076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Management of a Prostate Cancer Patient With Inherited Germline BRCA1 and BRCA2 Mutations: A Case Report.PMID 33556450Read ↗

Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations.Semantic proximity Read ↗

Clinical features and management of BRCA1 and BRCA2-associated prostate cancer.Semantic proximity Read ↗

The role of BRCA1 and BRCA2 in prostate cancer.Semantic proximity Read ↗

Male BRCA mutation carriers: clinical characteristics and cancer spectrum.Semantic proximity Read ↗

Breast cancer in a BRCA2 mutation carrier with a history of prostate cancer.Semantic proximity Read ↗

The relevance of BRCA genetics to prostate cancer pathogenesis and treatment.Semantic proximity Read ↗

Prostate Cancer in a Patient with a Family History of BRCA Mutation: a Case Report and Literature Review.Semantic proximity Read ↗

Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families.Semantic proximity Read ↗

High-Grade Prostate Adenocarcinoma in a BRCA2 Germline Mutation Carrier: Precision Oncology and Familial Cascade Testing: a case reportSemantic proximity Read ↗

BRCA2 gene mutation and prostate cancer risk. Comprehensive review and update.Semantic proximity Read ↗

BRCA Germline Mutations in Prostate Cancer: The Future Is TailoredSemantic proximity Read ↗

Review on the Role of BRCA Mutations in Genomic Screening and Risk Stratification of Prostate Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.