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Article

Detecting structure of haplotypes and local ancestry.

Genetics - 1 Mar 2014

Guan Yongtao

Abstract excerpt

We present a two-layer hidden Markov model to detect the structure of haplotypes for unrelated individuals. This allows us to model two scales of linkage disequilibrium (one within a group of haplotypes and one between groups), thereby taking advantage of rich haplotype information to infer local ancestry of admixed individuals. Our method outperforms competing state-of-the-art methods, particularly for regions...

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Identifiers

PMID: 24388880
DOI: 10.1534/genetics.113.160697
PMCID: PMC3948796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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