Article
[Construction and expression of six deletion mutants of human astrovirus C-terminal nsP1a/4 protein].
Bing du xue bao = Chinese journal of virology - 1 Sept 2013
Zhao Wei, Niu Ke, Zhao Jian, Jin Yi-ming, Sui Ting-ting, Wang Wen
Abstract excerpt
Human astrovirus (HAstV) is one of the leading causes of actue virual diarrhea in infants. HAstV-induced epithdlial cell apoptosis plays an important role in the pathogenesis of HAstV infection. Our previous study indicated that HAstV non-structural protein nsPla C-terminal protein nsPla/4 was the major apoptosis functional protein and probably contained the main apoptosis domains. In order to screen for...
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