Article
Genetic variants in 2q31 and 5p15 are associated with aggressive benign prostatic hyperplasia in a Chinese population.
The Prostate - 1 Aug 2013
Qi Jun, Tian Lu, Chen Zhuo, Wang Li, Tao Sha, Gu Xin, Na Rong, Jiao Yang, Kang Jian, Zheng Siqun, Xu Jianfeng, Sun Jielin
Abstract excerpt
BACKGROUND: Benign prostatic hyperplasia (BPH) is a common disease prevalent in elderly men. However, the genetic determinants of BPH remain unclear. Because BPH and prostate cancer (PCa) share some common pathological characteristics, we investigated whether susceptibility loci for PCa contributed to BPH risk and BPH aggressiveness in Chinese men. METHODS: Fourteen SNPs associated with PCa risk in a Chinese...
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