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Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

26 Oct 2018

Abstract excerpt

Abstract Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients and 280,541 controls of European ancestry, from Iceland and the UK. We discovered 23 genome-wide significant variants, located at 14 loci. There is little...

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PMID: 30410027
DOI: 10.1038/s41467-018-06920-9

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