Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.

Blood - 13 Mar 2014

Chambwe Nyasha, Kormaksson Matthias, Geng Huimin, De Subhajyoti, Michor Franziska, Johnson Nathalie A, Morin Ryan D, Scott David W, Godley Lucy A, Gascoyne Randy D, Melnick Ari, Campagne Fabien, Shaknovich Rita

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study, we carried out genomewide DNA methylation profiling of 140 DLBCL samples and 10 normal germinal center B cells using the HpaII tiny fragment enrichment by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Follow-Up Studies

Share to Gene Expression Regulation, Neoplastic

Share to Lymphoma, Large B-Cell, Diffuse

Share to Neoplasm Proteins

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 24385541
DOI: 10.1182/blood-2013-07-509885
PMCID: PMC3954051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.PMID 24385541Read ↗

DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphomaSemantic proximity Read ↗

The epigenetic basis of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere lengthSemantic proximity Read ↗

The many layers of epigenetic dysfunction in B-cell lymphomas.Semantic proximity Read ↗

Biological heterogeneity in diffuse large B-cell lymphomaSemantic proximity Read ↗

Beyond genomics - Targeting the epigenome in diffuse large B-cell lymphoma.Semantic proximity Read ↗

Epigenetic Symphony in Diffuse Large B-Cell Lymphoma: Orchestrating the Tumor MicroenvironmentSemantic proximity Read ↗

The EBV-Positive Tumor Methylome is Distinct from EBV-Negative in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Evolving insights into the genomic complexity and immune landscape of diffuse large B-cell lymphoma: opportunities for novel biomarkers.Semantic proximity Read ↗

Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphomaSemantic proximity Read ↗

Genetic heterogeneity of DLBCL, not otherwise specified.Semantic proximity Read ↗

Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.