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Article

Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition.

American journal of physiology. Lung cellular and molecular physiology - 15 Feb 2014

Vyas-Read Shilpa, Wang Wenyi, Kato Satomi, Colvocoresses-Dodds Jennifer, Fifadara Nimita H, Gauthier Theresa W, Helms My N, Carlton David P, Brown Lou Ann S

Abstract excerpt

Myofibroblast accumulation is a pathological feature of lung diseases requiring oxygen therapy. One possible source for myofibroblasts is through the epithelial-to-mesenchymal transition (EMT) of alveolar epithelial cells (AEC). To study the effects of oxygen on alveolar EMT, we used RLE-6TN and...

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Identifiers

PMID: 24375795
DOI: 10.1152/ajplung.00074.2013
PMCID: PMC3920228

Genes

SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24375795-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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