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Article

Gly126Arg substitution causes anomalous behaviour of α-skeletal and β-smooth tropomyosins during the ATPase cycle.

Archives of biochemistry and biophysics - 1 Feb 2014

Rysev Nikita A, Nevzorov Ilya A, Avrova Stanislava V, Karpicheva Olga E, Redwood Charles S, Levitsky Dmitrii I, Borovikov Yurii S

Abstract excerpt

To investigate how TM stabilization induced by the Gly126Arg mutation in skeletal α-TM or in smooth muscle β-TM affects the flexibility of TMs and their position on troponin-free thin filaments, we labelled the recombinant wild type and mutant TMs with 5-IAF and F-actin with FITC-phalloidin, inco...

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Identifiers

PMID: 24374033
DOI: 10.1016/j.abb.2013.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24374033-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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