Article
Antibacterial properties of recombinant human non-pancreatic secretory phospholipase A(2).
Biochemical and biophysical research communications - 15 Nov 2013
Qiu Shunchen, Lai Luhua
Abstract excerpt
Human non-pancreatic secretory phospholipase A2 (hnpsPLA2) is a group IIA phospholipase A2 which plays an important role in the innate immune response. This enzyme was found to exhibit bactericidal activity toward Gram-positive bacteria, but not Gram-negative ones. Though native hnpsPLA2 is active over a broad pH range, it is only highly active at alkaline conditions with the optimum activity pH of about 8.5. In...
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