Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2).

The Journal of biological chemistry - 29 Oct 2004

Nagiec Michal J, Lei Benfang, Parker Sarah K, Vasil Michael L, Matsumoto Masakado, Ireland Robin M, Beres Stephen B, Hoe Nancy P, Musser James M

Abstract excerpt

Group A Streptococcus (GAS) is an important human pathogen that causes many types of infections, including pharyngitis and severe invasive diseases. We recently sequenced the genome of a serotype M3 strain and identified a prophage-encoded secreted phospholipase A(2) designated SlaA. To study SlaA structure-activity relationships, 20 site-specific mutants were constructed by alanine-replacement mutagenesis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to Phospholipases A

Share to Prophages

Share to Streptococcus pyogenes

Share to Structure-Activity Relationship

Share to Substrate Specificity

Source

Identifiers

PMID: 15304506
DOI: 10.1074/jbc.M405434200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2).PMID 15304506Read ↗

Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A <sub>2</sub>Semantic proximity Read ↗

Bacterial phospholipases C with dual activity: phosphatidylcholinesterase and sphingomyelinaseSemantic proximity Read ↗

Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-l-alanine Amidase Driving the “Suicidal Tendencies” of Streptococcus pneumoniae—A ReviewSemantic proximity Read ↗

Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-L-alanine Amidase Driving the ‘Suicidal Tendencies’ of Streptococcus pneumoniae— A ReviewSemantic proximity Read ↗

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effectsSemantic proximity Read ↗

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effectsSemantic proximity Read ↗

Secreted bacterial phospholipase A2 enzymes: better living through phospholipolysisSemantic proximity Read ↗

Identification and characterisation a surface-associated arginine peptidase in Streptococcus suis serotype 2.Semantic proximity Read ↗

Inactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis.Semantic proximity Read ↗

Streptococcus pyogenes Phospholipase A2 Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice.Semantic proximity Read ↗

A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatumSemantic proximity Read ↗

FplA From <i>Fusobacterium nucleatum</i> is a Type Vd autotransporter phospholipase with a proposed role in altered host signaling and evasion of autophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.