Article
Phylogenetically resolving epidemiologic linkage.
Proceedings of the National Academy of Sciences of the United States of America - 8 Mar 2016
Romero-Severson Ethan O, Bulla Ingo, Leitner Thomas
Abstract excerpt
Although the use of phylogenetic trees in epidemiological investigations has become commonplace, their epidemiological interpretation has not been systematically evaluated. Here, we use an HIV-1 within-host coalescent model to probabilistically evaluate transmission histories of two epidemiologically linked hosts. Previous critique of phylogenetic reconstruction has claimed that direction of transmission is...
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