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Article

Pathogenesis and management of acute myeloid leukemia that has evolved from a myeloproliferative neoplasm

23 Dec 2013

Abstract excerpt

PURPOSE OF REVIEW: The myeloproliferative neoplasms (MPNs), including essential thrombocythemia, polycythemia vera and primary myelofibrosis (PMF), are a heterogeneous group of myeloid-derived chronic haematopoietic malignancies. Frequent clinical consequences of these diseases include not only an increased risk of thrombosis but also leukemic transformation, which carries a particularly poor prognosis. Here, we...

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PMID: 24366192
DOI: 10.1097/moh.0000000000000017

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