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Article

Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways.

Acta chimica Slovenica - 1 Jan 2013

Lewiñska Monika, Zmrzljak Ursula Prosenc, Rozman Damjana

Abstract excerpt

Lanosterol 14a-demethylase CYP51 is the most conserved cytochrome P450 (CYP) and is a part of hepatic cholesterol synthesis. Other liver CYPs contribute to cholesterol detoxification through bile acids or to xenobiotic detoxification (DM). To get novel insights into characteristics of the CYP51A1 locus that was so far not linked to human disorders we performed a meta-analysis of CYP51A1 gene polymorphisms in...

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PMID: 24362992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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