Article
Genetic determinants of neuroglobin transcription.
Neurogenetics - 1 Mar 2014
Wang R, Halper-Stromberg E, Szymanski-Pierce M, Bassett S S, Avramopoulos D
Abstract excerpt
Neuroglobin (NGB) is a neuron-specific vertebrate globin shown to protect against hypoxia, ischemia, oxidative stress and the toxic effects of Amyloid-beta. Following on our and others' results highlighting the importance of NGB expression in disease, we searched for genetic determinants of its expression. We found that a microRNA expressed with the NGB transcript shows significant target enrichments in the...
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