Article
Nano-graphene oxide as a novel platform for monitoring the effect of LNA modification on nucleic acid interactions.
The Analyst - 21 Feb 2014
Rana Muhit, Balcioglu Mustafa, Robertson Neil, Yigit Mehmet V
Abstract excerpt
Graphene oxide has gained significant attention due to its exceptional physical properties at biological interfaces. It has extraordinary quenching, fast adsorption and desorption properties that are suitable for detection of molecular interactions in nucleic acids. Here we studied the interaction between locked nucleic acid (LNA) modified oligonucleotides and its complementary miR-10b DNA analog. We demonstrate...
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