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Article

Evidence of the involvement of the DHFR gene in nonsyndromic cleft lip with or without cleft palate.

European journal of medical genetics - 1 Jan 2014

Martinelli Marcella, Girardi Ambra, Cura Francesca, Carinci Francesco, Morselli Paolo Giovanni, Scapoli Luca

Abstract excerpt

Studies aimed at evidencing genetic causes for neural tube defect (NTD) occurrence have often provided the inspiration for orofacial cleft aetiology investigations. The correlation between the two congenital malformations is provided by the similar incidence timing and the involvement of structures localized in the midline of the embryo. This connection is corroborated by the existence of a number of genes...

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Source

Identifiers

PMID: 24361572
DOI: 10.1016/j.ejmg.2013.12.002

Genes

DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence of the involvement of the DHFR gene in nonsyndromic cleft lip with or without cleft palate.PMID 24361572Read ↗

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