Article
Meta-analyses to investigate gene-environment interactions in neuroepidemiology.
Neuroepidemiology - 1 Jan 2014
van der Mei I A F, Otahal P, Simpson S, Taylor B, Winzenberg T
Abstract excerpt
BACKGROUND: Most chronic neurological diseases are caused by a combination of multiple genetic and environmental factors. Increasingly, gene-environment interactions (GxE) are being examined, providing opportunities to combine studies systematically using meta-analysis. METHODS: Systematic review of the literature on how to examine GxE using observational study designs, and how to conduct a meta-analysis of...
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