Article
Plectin-intermediate filament partnership in skin, skeletal muscle, and peripheral nerve.
Histochemistry and cell biology - 1 Jul 2013
Castañón Maria J, Walko Gernot, Winter Lilli, Wiche Gerhard
Abstract excerpt
Plectin is a large, 500-kDa, intermediate filament (IF)-associated protein. It acts as a cytoskeletal crosslinker and signaling scaffold, affecting mechanical as well as dynamic properties of the cytoskeleton. As a member of the plakin family of cytolinker proteins, plectin has a multidomain structure that is responsible for its vast binding portfolio. It not only binds to all types of IFs, actin filaments and...
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