Article
Association of specific haplotypes of GAS6 gene with stroke.
Thrombosis and haemostasis - 1 Aug 2007
Muñoz Xavier, Obach Víctor, Hurtado Begoña, de Frutos Pablo García, Chamorro Angel, Sala Núria
Abstract excerpt
The product of the growth arrest-specific gene 6 (GAS6), a ligand for tyrosine kinase receptors, is a vitamin K-dependent protein, structurally related to anticoagulant protein S. Gas6-deficient mice are protected against thrombosis, demonstrating the importance of this protein in the cardiovascular system. In a preliminary study on GAS6 polymorphisms and atherothrombotic disease we found an association between...
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