Article
Variation in the coding and 3' untranslated regions of the porcine prolactin receptor short form modifies protein expression and function.
Animal genetics - 1 Feb 2014
Trott Josephine F, Freking Bradley A, Hovey Russell C
Abstract excerpt
The actions of prolactin (PRL) are mediated by both long (LF) and short isoforms (SF) of the PRL receptor (PRLR). Here, we report on a genetic and functional analysis of the porcine PRLR (pPRLR) SF. Three single nucleotide polymorphisms (SNPs) within exon 11 of the pPRLR-SF give rise to four amino acid haplotypes of the intracellular domain. We identified the dimorphic insertion of a short interspersed repetitive...
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