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Article

Transcriptional Characterization of Porcine Leptin and Leptin Receptor Genes.

PloS one - 1 Jan 2013

Pérez-Montarelo Dafne, Fernández Almudena, Barragán Carmen, Noguera Jose L, Folch Josep M, Rodríguez M Carmen, Ovilo Cristina, Silió Luis, Fernández Ana I

Abstract excerpt

The leptin (LEP) and its receptor (LEPR) regulate food intake and energy balance through hypothalamic signaling. However, the LEP-LEPR axis seems to be more complex and its expression regulation has not been well described. In pigs, LEP and LEPR genes have been widely studied due to their relevance. Previous studies reported significant effects of SNPs located in both genes on growth and fatness traits. The aim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 23824082
DOI: 10.1371/journal.pone.0066398
PMCID: PMC3688923

Genes

LEPR
LEP

Variants

Provenance

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