Article
Sequence variation analysis of the prolactin receptor C-terminal region in women with premature ovarian failure.
Fertility and sterility - 1 Dec 2010
Bachelot Anne, Bouilly Justine, Liu Yuchen, Rebourcet Diane, Leux Céline, Kuttenn Frédérique, Touraine Philippe, Binart Nadine
Abstract excerpt
Using a mouse model expressing only the PRL receptor short isoform mimicking premature ovarian failure, signaling pathways induced by PRL were analyzed in mouse ovaries. Sequencing of the coding portion of exons 10 and 11, specific to the long and short receptor isoform, respectively, did not revealed any mutation in 101 women with premature ovarian failure.
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