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Plants and phytochemicals for Huntington′s disease

1 Jan 2013

Abstract excerpt

Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive motor dysfunction, including chorea and dystonia, emotional disturbances, memory, and weight loss. The medium spiny neurons of striatum and cortex are mainly effected in HD. Various hypotheses, including molecular genetics, oxidative stress, excitotoxicity, metabolic dysfunction, and mitochondrial impairment have been proposed...

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PMID: 24347915
DOI: 10.4103/0973-7847.120505

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